Selective Androgen Receptor Modulators (SARMs) have taken the bodybuilding world by storm, offering muscle growth and strength gains without the harsh side effects of anabolic steroids. Among the most popular are RAD 140 (Testolone) and its newer counterpart, RAD 150.
Both are known for their impressive anabolic properties, but they have key differences that can influence which one is best for your fitness goals. In this guide, we’ll break down how they work, their benefits, side effects, and which might be the better choice for you.
What is RAD 140?
How It Works
RAD 140 is a highly potent SARM that selectively binds to androgen receptors in muscle and bone tissue. This targeted action mimics testosterone’s anabolic effects without converting to estrogen or causing excessive androgenic side effects.
Benefits of RAD 140
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Accelerated Muscle Growth: Promotes lean mass development, making it ideal for bulking cycles.
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Strength Gains: Enhances power output, allowing for heavier lifts and better gym performance.
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Fat Reduction: Helps preserve lean muscle while cutting fat, making it useful for recomposition.
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Faster Recovery: Shortens downtime between intense workouts.
Side Effects of RAD 140
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Testosterone Suppression: Can lower natural hormone levels, requiring post-cycle therapy (PCT).
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Liver Strain: Some evidence suggests mild liver toxicity.
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Cardiovascular Effects: Potential impact on cholesterol levels, though less severe than steroids.
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What is RAD 150?
How It Works
RAD 150 is a chemically modified version of RAD 140, featuring an added ester chain. This structural change is designed to enhance bioavailability, prolong its effects, and improve safety. It still binds to androgen receptors with high affinity but may offer a smoother, longer-lasting impact.
Benefits of RAD 150
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Greater Potency: Some users report more pronounced muscle growth compared to RAD 140.
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Stronger Bone Density Support: Provides enhanced benefits for bone health.
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Improved Recovery: Works faster to heal microtears from intense training.
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Lower Testosterone Suppression: While suppression still occurs, it may be milder compared to RAD 140.
Side Effects of RAD 150
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Mild Suppression of Testosterone: PCT is still required but may be less aggressive than with RAD 140.
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Potential Lipid Changes: May impact cholesterol levels, similar to other SARMs.
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Possible Liver Effects: Less hepatotoxic than RAD 140 but still requires caution.
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Key Differences Between RAD 140 and RAD 150
Muscle Growth & Strength
Both SARMs are excellent for gaining lean mass, but RAD 150 may offer a slight edge in potency due to its modified structure.
Testosterone Suppression
RAD 140 has a higher tendency to suppress natural testosterone production, making RAD 150 the safer option in this regard.
Liver and Safety Profile
RAD 140 has shown mild liver toxicity, whereas RAD 150’s ester modification may reduce this effect, making it a better choice for those concerned about long-term health.
Cycle Length & Dosage
Both SARMs have similar cycle lengths (8–12 weeks), but RAD 150 may require lower dosing due to its increased bioavailability.
Which SARM is Better for Muscle Growth?
If your goal is pure muscle-building and strength gains, RAD 140 is a well-tested choice. However, RAD 150 could be a superior alternative for those seeking greater potency with fewer side effects.
When to Choose RAD 140:
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You want proven results for bulking and strength.
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You’re comfortable managing testosterone suppression.
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You’re stacking with other SARMs for a cutting cycle.
When to Choose RAD 150:
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You prefer a smoother anabolic effect with less suppression.
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You want longer-lasting benefits per dose.
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You’re looking for a safer option with lower liver strain.
Side Effects Comparison
Both SARMs can lead to minor side effects, but RAD 150’s structural enhancement provides an advantage:
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RAD 140: More testosterone suppression, potential liver stress.
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RAD 150: Milder suppression, lower liver toxicity.
Stacking Options
RAD 140 Stacking
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Ostarine (MK-2866): Ideal for lean muscle gains while cutting.
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Ligandrol (LGD-4033): Increases bulk and strength.
RAD 150 Stacking
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YK-11: Enhances muscle hypertrophy with additional myostatin inhibition.
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Ibutamoren (MK-677): Promotes growth hormone release for better recovery.
Who Should Use RAD 140 or RAD 150?
RAD 140 is Best For:
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Beginners & intermediate users wanting fast muscle growth.
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Athletes seeking explosive strength without steroids.
RAD 150 is Best For:
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Advanced users looking for higher potency and safety.
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Longer cycles with fewer side effects.
Legal Status & Safety Considerations
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Both SARMs are not FDA-approved for human use and are banned by WADA in competitive sports.
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Many sources sell counterfeit or underdosed products—always buy from reputable vendors.
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Proper PCT is required after any RAD 140 or RAD 150 cycle.
Conclusion
Both RAD 140 and RAD 150 offer impressive muscle-building potential, but they come with distinct pros and cons. RAD 140 remains a powerhouse for mass and strength, while RAD 150 introduces a more refined, safer approach. Choosing the right one depends on your goals, experience level, and tolerance for potential side effects.
If you’re looking for the most proven, widely used SARM with explosive gains, RAD 140 is the way to go. However, if you prefer a newer, safer alternative with longer-lasting effects, RAD 150 might be the better fit. Regardless of your choice, always prioritize health, quality sourcing, and proper post-cycle therapy.
Hi, I'm Dave Moffat the founder and Chief Editor of steroidsourcetalk.com and certified International Personal Trainer and Certified Nutritionist. My passion has always been bodybuilding but with 15 years' experience in weight loss programs too, it's hard not to mention all that when you're working at your fitness level fullest (I hope). When Im not in the gym or spending time away from my family i often think about what advice would help others achieve theirs goals just like these inspired mine.
